LMO2 at 25 years: a paradigm of chromosomal translocation proteins
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چکیده
منابع مشابه
LMO2 at 25 years: a paradigm of chromosomal translocation proteins
LMO2 was first discovered through proximity to frequently occurring chromosomal translocations in T cell acute lymphoblastic leukaemia (T-ALL). Subsequent studies on its role in tumours and in normal settings have highlighted LMO2 as an archetypical chromosomal translocation oncogene, activated by association with antigen receptor gene loci and a paradigm for translocation gene activation in T-...
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ژورنال
عنوان ژورنال: Open Biology
سال: 2015
ISSN: 2046-2441
DOI: 10.1098/rsob.150062